Medicinal Chemistry
We are specialized in early-stage drug discovery services, and our programs begin with the identification of biologically relevant therapeutic targets. We design and synthesize numerous candidate molecules with the goal of discovering clinical leads that selectively interact with target receptors or enzymes and modulate their activity.
Our Key Services Include:
- Target Identification and Validation: Finding specific biological molecules or genes tied to a disease and demonstrating they can be altered by a drug.
- Hit Identification and Screening: Testing large libraries of chemical compounds with automated systems to pinpoint those interacting with disease targets.
- Hit-to-Lead Development: Enhancing initial active chemical compounds (hits) to increase their stability, selectivity, and potency.
- Lead Optimization: Refining molecular structures to maximize therapeutic benefits while minimizing toxic side effects.
- Preclinical Evaluation: Conducting early laboratory and animal safety assessments to evaluate how the body processes the drug prior to clinical trials.